S-adenosyl-L-methionine (SAMe) is a key biological factor that drives a wide variety of essential biochemical reactions, including the methylation of DNA, catecholamine neurotransmitters (brain messenger-molecules), phospholipids, hormones, and chondrocytes (cartilage-forming cells). Research supports SAMe’s ability to support healthy mood function and helps relieve osteoarthritic pain. SAMe may be prescribed by your Medicor physician as part of your treatment. In this case it is not HST taxable. Please see Excise Tax Act for details.